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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERO1L All Species: 36.06
Human Site: S115 Identified Species: 49.58
UniProt: Q96HE7 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96HE7 NP_055399.1 468 54393 S115 E V P D G I K S A S Y K Y S E
Chimpanzee Pan troglodytes XP_509950 468 54427 S115 E V P D G I K S A S Y K Y S E
Rhesus Macaque Macaca mulatta XP_001103965 468 54383 S115 E V P D G I K S A S Y K Y S E
Dog Lupus familis XP_547813 468 54343 S115 E V P D G I K S A S Y K Y S E
Cat Felis silvestris
Mouse Mus musculus Q8R180 464 54066 S115 E V P D G I K S A S Y K Y S E
Rat Rattus norvegicus Q8R4A1 464 54000 S115 E V P D G I K S A S Y K Y S K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515503 465 53870 S112 E V P D G I K S S S Y K Y S E
Chicken Gallus gallus XP_421473 463 52908 S113 E V P D G I R S A G Y K Y S E
Frog Xenopus laevis Q6DD71 465 53720 P111 E V P G F K P P G F K Y T E E
Zebra Danio Brachydanio rerio Q7T3D1 489 56571 S107 E V P E G L K S S S Y K Y S E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3A6 483 55641 D124 A I P Q G I K D K G E H K E K
Honey Bee Apis mellifera XP_623933 471 55049 G119 D I P D G L K G D I L R N V H
Nematode Worm Caenorhab. elegans Q7YTU4 478 55136 R109 V P A G L R R R N A V N M E A
Sea Urchin Strong. purpuratus XP_796844 897 101920 E532 D L P C G L K E E S N E N K Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C7S7 469 53812 K138 E F P E P F K K P F V P G L P
Baker's Yeast Sacchar. cerevisiae Q03103 563 65014 W120 W D T L P E Y W Q P E I L G S
Red Bread Mold Neurospora crassa Q7SEY9 668 75589 V108 N E E D I P E V W R A K E L G
Conservation
Percent
Protein Identity: 100 99.5 98.7 96.3 N.A. 91.8 91.4 N.A. 84.6 77.7 70.9 62.1 N.A. 46.1 48.4 41.4 29.3
Protein Similarity: 100 99.5 99.3 97.8 N.A. 95.9 95.7 N.A. 90.1 85.4 83.9 75.4 N.A. 64.1 65.6 60.8 37.6
P-Site Identity: 100 100 100 100 N.A. 100 93.3 N.A. 93.3 86.6 26.6 80 N.A. 26.6 26.6 0 26.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 93.3 26.6 100 N.A. 40 53.3 13.3 53.3
Percent
Protein Identity: N.A. N.A. N.A. 37.9 22.5 22.1
Protein Similarity: N.A. N.A. N.A. 55.6 41.2 38
P-Site Identity: N.A. N.A. N.A. 20 0 13.3
P-Site Similarity: N.A. N.A. N.A. 26.6 0 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 0 6 0 0 0 0 0 42 6 6 0 0 0 6 % A
% Cys: 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 12 6 0 59 0 0 0 6 6 0 0 0 0 0 0 % D
% Glu: 65 6 6 12 0 6 6 6 6 0 12 6 6 18 53 % E
% Phe: 0 6 0 0 6 6 0 0 0 12 0 0 0 0 0 % F
% Gly: 0 0 0 12 71 0 0 6 6 12 0 0 6 6 6 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 6 0 0 6 % H
% Ile: 0 12 0 0 6 53 0 0 0 6 0 6 0 0 0 % I
% Lys: 0 0 0 0 0 6 71 6 6 0 6 59 6 6 12 % K
% Leu: 0 6 0 6 6 18 0 0 0 0 6 0 6 12 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 6 0 0 % M
% Asn: 6 0 0 0 0 0 0 0 6 0 6 6 12 0 0 % N
% Pro: 0 6 83 0 12 6 6 6 6 6 0 6 0 0 6 % P
% Gln: 0 0 0 6 0 0 0 0 6 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 6 12 6 0 6 0 6 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 53 12 53 0 0 0 53 6 % S
% Thr: 0 0 6 0 0 0 0 0 0 0 0 0 6 0 0 % T
% Val: 6 59 0 0 0 0 0 6 0 0 12 0 0 6 0 % V
% Trp: 6 0 0 0 0 0 0 6 6 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 6 0 0 0 53 6 53 0 6 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _